Season 16

E1. Jarod Miller, Jason Lezak, Ra Ra Riot

Sep 2, 2008 · 45m

E2. Nicolas Cage, Vivica A. Fox, Delta Spirit

Sep 3, 2008 · 45m

E3. Dr. Phil, Kevin Connolly, Adele

Sep 4, 2008 · 45m

E4. Jerry O'Connell, Tim Gunn, Christian Lander

Sep 5, 2008 · 45m

E5. Howie Mandel, Nastia Liukin, Bon Iver

Sep 8, 2008 · 45m

E6. Keira Knightley, Tyler Perry, Bill Burr

Sep 9, 2008 · 45m

E7. Curtis Jackson, Kaitlin Olson, Gym Class Heroes

Sep 10, 2008 · 45m

E8. Serena Williams, Amy Sedaris, Meiko

Sep 11, 2008 · 45m

E9. Eva Mendes, Luke Russert, The Fab Faux

Sep 12, 2008 · 45m

Tonight's guests include Eva Mendes and Luke Russert. The Fab Faux perform.

E10. Samuel L. Jackson, Ricky Gervais, Marc Broussard

Sep 15, 2008 · 45m

Tonight's guests include Samuel L. Jackson and Ricky Gervais. Marc Broussard performs.

E11. Martha Stewart, Harland Williams, Kasey Chambers & Shane Nicholson

Sep 16, 2008 · 45m

Tonight's guests include Martha Stewart and Harland Williams. Kasey Chambers & Shane Nicholson perform.

E12. Ray Liotta, Marc Maron,Loudon Wainwright III

Sep 17, 2008 · 45m

Tonight's guests include Ray Liotta and Marc Maron. Loudon Wainwright III performs.

E13. Anderson Cooper,Willie Nelson, Southside Johnny with La Bamba's Big Band

Sep 18, 2008 · 45m

Tonight's guests include Anderson Cooper and Willie Nelson. Southside Johnny with La Bamba's Big Band perform.

E14. Ice-T, Dwayne Wade, Shane Mauss

Sep 19, 2008 · 45m

Tonight's guests include Ice-T and Dwayne Wade. Shane Mauss performs.

E15. Diane Lane, Patton Oswalt, Little Feat

Sep 22, 2008 · 45m

Tonight's guests include Diane Lane and Patton Oswalt. Little Feat perform.

E16. Billy Bob Thornton, Aasif Mandvi, Kenny Shopsin

Sep 23, 2008 · 45m

Tonight's guests include Billy Bob Thornton and Aasif Mandvi. Kenny Shopsin performs.

E17. Jaime Pressly, Little Britain, Lenka Kripac

Sep 24, 2008 · 45m

Tonight's guests include Jamie Pressly and Little Britain. Lenka Kripac performs.

E18. Julianne Moore, Zachary Levi, Jakob Dylan

Sep 25, 2008 · 45m

Tonight's guests include Julianne Moore and Zachary Levi. Jakob Dylan performs.

E19. Brooke Shields, Robert Reich, Amos Lee

Sep 26, 2008 · 45m

Tonight's guests include Brooke Shields and Robert Reich. Amos Lee performs.

E20. Bill Maher, Simon Pegg, The Watson Twins

Sep 29, 2008 · 45m

Tonight's guests include Bill Maher and Simon Pegg. The Watson Twins perform.

E21. Julia Louis-Dreyfus, Michael Cera, Nate Bargatze

Sep 30, 2008 · 45m

E22. Robin Wright-Penn, Louis C.K., Department of Eagles

Oct 1, 2008 · 45m

Tonight's guests include Robin Wright-Penn and Louis C.K.. Department of Eagles perform.

E23. Tom Arnold, Flavor Flav, Ben Folds

Oct 2, 2008 · 45m

Tonight's guests include Tom Arnold and Flavor Flav. Ben Folds performs "You Don't Know Me" with Regina Spektor.

E24. Greg Kinnear. J.J. Abrams, Nick Cave and the Bad Seeds

Oct 3, 2008 · 45m

E25. Felicity Huffman, Jason Sudeikis, Jenny Lewis

Oct 6, 2008 · 45m

Tonight's guests include Felicity Huffman and Jason Sudeikis. Jenny Lewis performs.

E26. Russell Crowe, Alicia Keys, Death Cab for Cutie

Oct 7, 2008 · 45m

Tonight's guests include Russell Crowe and Alicia Keys. Death Cab For Cutie perform.

E27. Molly Shannon, Jason Ritter, Noah McCullough

Oct 8, 2008 · 45m

Tonight's guests include Molly Shannon, Jason Ritter and Noah McCullough.

E28. Dennis Quaid, Lance Mackey, Sarah McLachlan

Oct 9, 2008 · 45m

Tonight's guests include Dennis Quaid and Lance Mackey. Sarah McLachlan performs.

E29. LL Cool J, Oliver Stone, Dead Confederates

Oct 10, 2008 · 45m

Tonight's guests include LL Cool J and Oliver Stone. Dead Confederates perform.

E30. Christian Slater, Brian Posehn, Flobots

Oct 13, 2008 · 45m

Tonight's guests include Christian Slater and Brian Posehn. Flobots perform.